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Chemically Mediated Discogenic Pain is closely related to Degenerative Disc Disease. Some researchers believe that CMDPS is the early version of DDD. In CMDPS, certain enzymes leak out of the intervertebral disc. The principle enzyme is called Phospholipase A2 (PLA2). Those enzymes cause the nerves near the spine to be hypersensitive. When nerves become hypersensitive, […]